| 2012 NL Leaders | |||||||||||||
| Name | Age | Team | G | IP | TBF | BB% | K% | BABIP | LOB% | GB% | HR/Air | ERA | FIP |
| Kristopher Medlen | 27 | Atlanta | 50 | 138.00 | 520 | 4.4% | 23.1% | .262 | 85% | 55% | 4% | 1.57 | 2.45 |
| Ryan Dempster | 35 | Chi Cubs | 16 | 104.00 | 417 | 6.5% | 19.9% | .241 | 84% | 43% | 5% | 2.25 | 3.46 |
| R.A. Dickey | 38 | NY Mets | 34 | 233.67 | 927 | 5.8% | 24.8% | .284 | 80% | 47% | 7% | 2.73 | 3.30 |
| Cliff Lee | 34 | Philadelphia | 30 | 211.00 | 847 | 3.3% | 24.4% | .313 | 79% | 46% | 8% | 3.16 | 3.17 |
| Matt Cain | 28 | San Francisco | 32 | 219.33 | 876 | 5.8% | 22.0% | .269 | 79% | 40% | 6% | 2.79 | 3.43 |
| Johnny Cueto | 26 | Cincinnati | 33 | 217.00 | 888 | 5.5% | 19.1% | .304 | 79% | 49% | 5% | 2.78 | 3.30 |
| Jordan Zimmermann | Washington | 32 | 195.67 | 805 | 5.3% | 19.0% | .295 | 79% | 44% | 5% | 2.94 | 3.54 | |
| Clayton Kershaw | 24 | LA Dodgers | 33 | 227.67 | 901 | 7.0% | 25.4% | .275 | 78% | 47% | 5% | 2.53 | 2.93 |
| Yovani Gallardo | 26 | Milwaukee | 33 | 204.00 | 860 | 9.4% | 23.7% | .301 | 78% | 47% | 9% | 3.66 | 3.98 |
| Joshua Collmenter | Arizona | 28 | 90.33 | 375 | 5.9% | 21.3% | .312 | 78% | 40% | 8% | 3.69 | 3.96 | |
| Cole Hamels | 29 | Philadelphia | 31 | 215.33 | 867 | 6.0% | 24.9% | .298 | 78% | 44% | 7% | 3.09 | 3.34 |
| Kyle Lohse | 34 | St. Louis | 33 | 211.00 | 864 | 4.4% | 16.6% | .270 | 77% | 41% | 5% | 2.86 | 3.54 |
| Bronson Arroyo | 35 | Cincinnati | 32 | 202.00 | 835 | 4.2% | 15.4% | .292 | 77% | 43% | 7% | 3.74 | 4.12 |
| Ryan Vogelsong | 35 | San Francisco | 31 | 189.67 | 788 | 7.9% | 20.1% | .293 | 76% | 43% | 5% | 3.37 | 3.73 |
| Lance Lynn | 25 | St. Louis | 35 | 176.00 | 744 | 8.6% | 24.2% | .328 | 76% | 46% | 6% | 3.78 | 3.53 |
| Jonathon Niese | 26 | NY Mets | 30 | 190.33 | 788 | 6.2% | 19.7% | .279 | 76% | 49% | 7% | 3.40 | 3.84 |
| Paul Maholm | 30 | Chi Cubs | 21 | 120.33 | 503 | 6.8% | 16.1% | .290 | 76% | 50% | 6% | 3.74 | 4.17 |
| Stephen Strasburg | Washington | 28 | 159.33 | 653 | 7.4% | 30.2% | .320 | 75% | 43% | 7% | 3.16 | 2.86 | |
| Matthew Latos | 25 | Cincinnati | 33 | 209.33 | 858 | 7.5% | 21.6% | .275 | 75% | 46% | 8% | 3.48 | 3.89 |
| Shaun Marcum | 31 | Milwaukee | 21 | 124.00 | 527 | 7.8% | 20.7% | .288 | 75% | 36% | 7% | 3.70 | 4.14 |
| Ian Kennedy | 28 | Arizona | 33 | 208.33 | 899 | 6.1% | 20.8% | .316 | 75% | 38% | 7% | 4.02 | 4.07 |
| Matt Garza | 29 | Chi Cubs | 18 | 103.67 | 424 | 7.5% | 22.6% | .275 | 74% | 50% | 10% | 3.91 | 4.20 |
| Eric Stults | 33 | San Diego | 18 | 92.33 | 383 | 6.0% | 13.3% | .275 | 74% | 39% | 4% | 3.22 | 3.79 |
| Joe Kelly | St. Louis | 24 | 107.00 | 457 | 7.9% | 16.4% | .310 | 74% | 52% | 6% | 3.53 | 4.03 | |
| Chris Young | 33 | NY Mets | 20 | 115.00 | 493 | 7.3% | 16.2% | .301 | 74% | 24% | 6% | 4.15 | 4.54 |
| Thomas Hanson | 26 | Atlanta | 31 | 174.67 | 761 | 9.3% | 21.2% | .324 | 74% | 40% | 9% | 4.48 | 4.60 |
| A.J. Burnett | 36 | Pittsburgh | 31 | 202.33 | 851 | 7.3% | 21.2% | .301 | 74% | 58% | 7% | 3.51 | 3.56 |
| Gio Gonzalez | 27 | Washington | 32 | 199.33 | 822 | 9.2% | 25.2% | .276 | 74% | 49% | 3% | 2.89 | 2.86 |
| Kyle Kendrick | 28 | Philadelphia | 37 | 159.33 | 674 | 7.3% | 17.2% | .287 | 74% | 46% | 7% | 3.90 | 4.36 |
| Chris Capuano | 34 | LA Dodgers | 33 | 198.33 | 817 | 6.6% | 19.8% | .293 | 73% | 41% | 7% | 3.63 | 3.98 |
