| 2012 NL Leaders | |||||||||||||
| Name | Age | Team | G | IP | TBF | BB% | K% | BABIP | LOB% | GB% | HR/Air | ERA | FIP |
| Joshua Collmenter | Arizona | 28 | 90.33 | 375 | 5.9% | 21.3% | .312 | 78% | 40% | 8% | 3.69 | 3.96 | |
| Jeff Karstens | 30 | Pittsburgh | 19 | 90.67 | 372 | 4.0% | 17.7% | .295 | 68% | 38% | 4% | 3.97 | 3.35 |
| Jeremy Guthrie | 33 | Colorado | 19 | 90.67 | 422 | 7.3% | 10.7% | .328 | 67% | 43% | 11% | 6.35 | 6.40 |
| Eric Stults | 33 | San Diego | 18 | 92.33 | 383 | 6.0% | 13.3% | .275 | 74% | 39% | 4% | 3.22 | 3.79 |
| Randall Delgado | 22 | Atlanta | 18 | 92.67 | 401 | 10.5% | 19.0% | .313 | 70% | 50% | 6% | 4.37 | 4.10 |
| Jason Marquis | 34 | San Diego | 15 | 93.67 | 401 | 7.0% | 19.7% | .297 | 68% | 50% | 10% | 4.04 | 4.31 |
| Jeremy Hefner | NY Mets | 26 | 93.67 | 408 | 4.4% | 15.2% | .325 | 64% | 45% | 5% | 5.09 | 3.69 | |
| Drew Pomeranz | Colorado | 22 | 96.67 | 434 | 10.6% | 19.1% | .304 | 71% | 42% | 8% | 4.93 | 4.84 | |
| Anthony Bass | San Diego | 24 | 97.00 | 411 | 9.5% | 19.5% | .288 | 61% | 50% | 7% | 4.73 | 4.06 | |
| Alex White | Colorado | 23 | 98.00 | 459 | 11.1% | 13.9% | .324 | 69% | 54% | 9% | 5.51 | 5.26 | |
| Matt Garza | 29 | Chi Cubs | 18 | 103.67 | 424 | 7.5% | 22.6% | .275 | 74% | 50% | 10% | 3.91 | 4.20 |
| Ryan Dempster | 35 | Chi Cubs | 16 | 104.00 | 417 | 6.5% | 19.9% | .241 | 84% | 43% | 5% | 2.25 | 3.46 |
| J.A. Happ | 30 | Houston | 18 | 104.33 | 457 | 8.5% | 21.4% | .324 | 73% | 46% | 10% | 4.83 | 4.52 |
| Joe Kelly | St. Louis | 24 | 107.00 | 457 | 7.9% | 16.4% | .310 | 74% | 52% | 6% | 3.53 | 4.03 | |
| Patrick Corbin | Arizona | 22 | 107.00 | 454 | 5.5% | 18.9% | .326 | 71% | 47% | 8% | 4.54 | 4.03 | |
| Dillon Gee | NY Mets | 17 | 109.67 | 463 | 6.3% | 21.0% | .305 | 69% | 52% | 8% | 4.10 | 3.74 | |
| Christopher Volstad | 26 | Chi Cubs | 21 | 111.33 | 507 | 8.5% | 12.0% | .330 | 64% | 51% | 8% | 6.31 | 5.14 |
| Jeff Francis | 32 | Colorado | 24 | 113.00 | 502 | 4.4% | 15.1% | .358 | 68% | 51% | 8% | 5.58 | 4.30 |
| Chris Young | 33 | NY Mets | 20 | 115.00 | 493 | 7.3% | 16.2% | .301 | 74% | 24% | 6% | 4.15 | 4.54 |
| Johan Santana | 33 | NY Mets | 21 | 117.00 | 499 | 7.8% | 22.2% | .308 | 69% | 35% | 8% | 4.85 | 4.12 |
| Paul Maholm | 30 | Chi Cubs | 21 | 120.33 | 503 | 6.8% | 16.1% | .290 | 76% | 50% | 6% | 3.74 | 4.17 |
| Jaime Garcia | 26 | St. Louis | 20 | 121.67 | 515 | 5.8% | 19.0% | .353 | 69% | 54% | 4% | 3.92 | 3.00 |
| Zack Greinke | 29 | Milwaukee | 21 | 123.00 | 504 | 5.6% | 24.2% | .328 | 72% | 54% | 4% | 3.44 | 2.57 |
| Shaun Marcum | 31 | Milwaukee | 21 | 124.00 | 527 | 7.8% | 20.7% | .288 | 75% | 36% | 7% | 3.70 | 4.14 |
| Erik Bedard | 33 | Pittsburgh | 24 | 125.67 | 557 | 10.1% | 21.2% | .322 | 67% | 45% | 7% | 5.01 | 4.11 |
| Michael Fiers | Milwaukee | 23 | 127.67 | 539 | 6.7% | 25.0% | .325 | 73% | 34% | 5% | 3.74 | 3.13 | |
| Joe Saunders | 31 | Arizona | 21 | 130.00 | 561 | 5.5% | 15.9% | .312 | 72% | 44% | 7% | 4.22 | 4.22 |
| Wandy Rodriguez | 34 | Houston | 21 | 130.67 | 558 | 5.7% | 15.9% | .293 | 68% | 51% | 6% | 3.79 | 3.84 |
| Vance Worley | 25 | Philadelphia | 23 | 133.00 | 590 | 8.0% | 18.1% | .358 | 73% | 45% | 5% | 4.26 | 3.89 |
| Joe Blanton | 32 | Philadelphia | 21 | 133.33 | 560 | 3.2% | 20.5% | .304 | 67% | 43% | 9% | 4.59 | 4.02 |
