| 2010 NL Leaders | |||||||||||||
| Name | Age | Team | G | IP | TBF | BB% | K% | BABIP | LOB% | GB% | HR/Air | ERA | FIP |
| Bob Howry | 37 | Arizona | 14 | 14.33 | 67 | 9.0% | 9.0% | .255 | 45% | 26% | 15% | 10.68 | 8.97 |
| Marco Estrada | 27 | Milwaukee | 7 | 11.33 | 58 | 10.3% | 22.4% | .324 | 48% | 27% | 11% | 9.53 | 6.11 |
| Chad Qualls | 32 | Arizona | 43 | 38.00 | 190 | 7.9% | 17.9% | .448 | 51% | 54% | 8% | 8.29 | 4.30 |
| Bob Howry | 37 | Chi Cubs | 24 | 20.67 | 101 | 6.9% | 7.9% | .333 | 51% | 37% | 4% | 5.66 | 4.61 |
| Kyle Farnsworth | 34 | Atlanta | 23 | 20.00 | 82 | 8.5% | 30.5% | .295 | 52% | 39% | 7% | 5.40 | 2.96 |
| Charlie Morton | 27 | Pittsburgh | 17 | 79.67 | 382 | 6.8% | 15.4% | .373 | 53% | 45% | 10% | 7.57 | 5.32 |
| LaTroy Hawkins | 38 | Milwaukee | 18 | 16.00 | 74 | 8.1% | 24.3% | .432 | 53% | 47% | 8% | 8.44 | 3.99 |
| Charlie Haeger | 27 | LA Dodgers | 9 | 30.00 | 151 | 17.2% | 19.9% | .364 | 54% | 43% | 7% | 8.40 | 5.55 |
| D.J. Carrasco | 33 | Arizona | 18 | 22.67 | 98 | 12.2% | 20.4% | .283 | 54% | 52% | 3% | 3.18 | 3.64 |
| Wilfredo Ledezma | 30 | Pittsburgh | 27 | 19.67 | 92 | 6.5% | 23.9% | .377 | 55% | 38% | 5% | 6.86 | 3.27 |
| Cesar Valdez | 25 | Arizona | 9 | 20.00 | 97 | 10.3% | 13.4% | .391 | 56% | 57% | 7% | 7.65 | 4.76 |
| Ryota Igarashi | 31 | NY Mets | 34 | 30.33 | 135 | 13.3% | 18.5% | .298 | 56% | 39% | 7% | 7.12 | 4.96 |
| Esmil Rogers | 25 | Colorado | 28 | 72.00 | 333 | 7.8% | 19.8% | .397 | 56% | 50% | 4% | 6.13 | 3.47 |
| Jeff Samardzija | 26 | Chi Cubs | 7 | 19.33 | 100 | 20.0% | 9.0% | .266 | 56% | 30% | 8% | 8.38 | 8.29 |
| Brian Bruney | 28 | Washington | 19 | 17.67 | 93 | 21.5% | 17.2% | .385 | 58% | 44% | 3% | 7.64 | 5.43 |
| Billy Buckner | 27 | Arizona | 3 | 13.00 | 72 | 6.9% | 15.3% | .449 | 58% | 47% | 14% | 11.08 | 7.04 |
| Samuel Demel | 25 | Arizona | 37 | 37.00 | 165 | 7.3% | 20.0% | .333 | 58% | 53% | 9% | 5.59 | 4.14 |
| Adam Russell | 27 | San Diego | 12 | 15.67 | 63 | 7.9% | 28.6% | .378 | 58% | 47% | 0% | 4.02 | 1.77 |
| Wesley Wright | 26 | Houston | 14 | 33.00 | 148 | 8.8% | 19.6% | .330 | 58% | 44% | 10% | 5.73 | 5.17 |
| Mike Lincoln | 35 | Cincinnati | 19 | 19.67 | 94 | 10.6% | 12.8% | .353 | 59% | 52% | 3% | 7.32 | 4.38 |
| Felipe Paulino | 27 | Houston | 19 | 91.67 | 411 | 11.2% | 20.2% | .347 | 59% | 44% | 3% | 5.11 | 3.47 |
| Jeff Suppan | 36 | Milwaukee | 15 | 31.00 | 148 | 8.1% | 12.2% | .434 | 59% | 40% | 6% | 7.84 | 4.89 |
| Kyle Lohse | 32 | St. Louis | 18 | 92.00 | 431 | 8.1% | 12.5% | .376 | 60% | 43% | 5% | 6.55 | 4.45 |
| Christopher Leroux | 26 | Florida | 17 | 18.00 | 84 | 13.1% | 21.4% | .469 | 60% | 53% | 4% | 7.00 | 3.67 |
| James Russell | 24 | Chi Cubs | 57 | 49.00 | 219 | 5.0% | 19.2% | .306 | 60% | 28% | 9% | 4.96 | 5.24 |
| John Grabow | 32 | Chi Cubs | 28 | 25.67 | 126 | 10.3% | 15.9% | .349 | 60% | 43% | 10% | 7.36 | 5.72 |
| Sean Gallagher | 25 | Pittsburgh | 31 | 34.33 | 163 | 13.5% | 13.5% | .324 | 60% | 48% | 3% | 6.03 | 4.60 |
| Brad Lincoln | 25 | Pittsburgh | 11 | 52.67 | 240 | 6.3% | 10.4% | .318 | 60% | 38% | 7% | 6.66 | 5.52 |
| Mike MacDougal | 33 | St. Louis | 17 | 18.67 | 92 | 13.0% | 15.2% | .355 | 61% | 54% | 3% | 7.23 | 4.40 |
| Doug Davis | 35 | Milwaukee | 8 | 38.33 | 191 | 11.0% | 17.8% | .395 | 61% | 48% | 9% | 7.51 | 5.25 |
